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Cortifoam Foam is used for: Related Video Video preview Rheumatoid Arthritis Learn the signs of RA and how to relieve the pain. Treating inflammation of the rectum. Cortifoam Foam is a topical corticosteroid. It works by depressing the formation, release, and activity of different cells and chemicals that cause swelling, redness, and itching. Do NOT use Cortifoam Foam if: * you are allergic to any ingredient in Cortifoam Foam * you have a rectal obstruction, abscess, or perforation; irritation of the of peritoneum (lining of the abdomen); or fistulas * you are taking mifepristone Contact your doctor or health care provider right away if any of these apply to you. Before using Cortifoam Foam: Some medical conditions may interact with Cortifoam Foam. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you: * if you are pregnant, planning to become pregnant, or are breast-feeding * if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement * if you have allergies to medicines, foods, or other substances * if you have a parasitic, bacterial, fungal, or viral infection; diabetes; diarrhea; swelling of the esophagus; stomach problems; blockage or the intestine or other intestinal problems; measles; tuberculosis (TB); a positive TB skin test; chicken pox; shingles; herpes infection of the eye; ulcers; kidney problems; high blood pressure; thyroid problems; or you have received a recent vaccination * if you have a history of heart failure or heart attack